Although the technology in medicine is already very advanced, the use of plants that become the raw material for traditional medicine keeps is encouraged. Because, it turns out that plants have a variety of benefits that may not be found before.
Based on one study conducted by Gadjah Mada University (UGM), plants (Andrographis paniculata) sambiloto is herbal remedy for treating diabetes mellitus. According to one member of the research team Supreme Endro Nugroho, of the results of percobaanya performed on mice are known to contain diverse sambiloto leaf substances which can be used to overcome the disease
One of them, go great, was andrografolid. “Andrografolid with the main phytochemical components capable of lowering blood glucose levels and GLUT-4 expression in mice type 1 DM,” said Agung, as quoted from the website of the UNIVERSITY
Even though this new research conducted on mice, Professor of Faculty of Pharmacy GADJAH MADA UNIVERSITY was declared, giving of isolates Andrografolid or herbaceous extracts Sambiloto terpurifikasi for five days showed the hypoglycemic activity of poten in mice of Diabetes Mellitus with Insulin resistance. “Both also lowers LDL levels poten and triglycerides, but not effect conferring against cholesterol levels and body weight of a rat,” he said.
The combination of extract of terpurifikasi with metformin showed lower DM activities compared his usage. It drew from these findings, Andrografolid and extract of sambiloto lowers blood glucose levels in mice DM type 2 insulin resistance through increased expression of GLUT4 protein in muscle tissue.
In the Great opportunity also delivered a new drug, the findings of the wealth of biodiversity that posses Indonesia its potential is large enough. The reason, Indonesia incoming biodiversity sequence number two in the world after Brazil.
“However, the majority (over 90 percent) of the medicines and materials raw materials still imports. Only 300-an species that are utilized as part of the remedy, “imbuh the great.
The representative of the record field of study and devotion to Society UGM Suratman adds, the industry research activities in the UNIVERSITY is the implementation of the concept of pentahelix which is a development of the concept of the triple-helix in the form of academic, business-government that added the other two elements namely financing institutions and development agencies or professional societies. “Without the support of a sustainable financing and the appropriate expertise then the results of the research will not be up to the users appropriately and comprehensively,” said Suparman.
Suratman added, researchers at GMU directed able to give positive added value against the institutional role in performing basic tasks and functions as the central institution of innovation. Including the results of the research industry to be utilized for the construction of well-being society widely through the application of the research industry.
Sambiloto including one herbal remedy that has been researched scientifically improved by researchers. Sambiloto also include herbal remedies that are already widely utilized to treat some diseases, in the form of modern packaging.
Sambiloto, as can be read in Wikipedia, known in different names, among others, sambilata (Malay); ampadu land (West Sumatra); sambiloto, ki pait, Ziziphus mauritiana, andiloto (Central Java); Ki oray (Sundanese); pepaitan (Madura).
medicine herb sambiloto (sambiloto herbs tea)
In India and surrounding areas, the plant is known in different names, including chooraita (Punjabi), kalmeg (Bengali), kariyatu (Gujarati), kirayat (Hindi). In mainland China, the plant is called chuan xin lien. In the language of the United Kingdom, the plant is known by the name of green chirayta, creat, king of bitters, or Indian echinacea. Various names were United by the scientific name Andrographis paniculata (Burm. f.) Wall. ex Nees, which applies internationally.
The drug is efficacious plant Sambiloto be terna upright height can reach 90 centimeters. Originally suspected of the tropical regions of Asia. The spread of India extends to the South until in Siam, eastward to the Malay Peninsula, was later found in Java.
Sambiloto grow well in the lowlands up to an altitude of 700 metres above sea level, with a rainfall of 2,000-3,000 mm per year and the temperature 25-32 degrees centigrade.
Bambang Pujiasmanto, Faculty of agriculture Faculty of UNS, in research for his dissertation, entitled “strategy for the improvement of the Status of Plants Sambiloto (Andrographis paniculata Ness.) Into Plant Cultivation “, mentions the community utilize the header section (leaf and stem) plants sambiloto as traditional medicine to cure the amplifier, drug fever, dysentery, cholera, diabetes, Lung pain, influenza, and bronchitis.
Wikipedia mentions also utilized this plant community in order to prevent the formation of ulcers, smoothen the urine (diuretika) and exposed to toxins.
Potassium compounds provide the benefits of lowering blood pressure. Pharmacological experiment results showed water decoction of leaves of sambiloto 10 percent with a rate of 0.3 ml/kg body weight can provide a decrease in blood sugar levels that are comparable to the grant suspension glibenclamid.
Leaf sambiloto is also believed to be used as a cure of the disease typhoid by taking 10-15 leaves boiled to boiling water for drinking and rebusannya.
Lecturer and one of the members of the research team from sambiloto Faculty of Pharmacy Gadjah Mada University, Prof. Dr. Endro Agung Nugroho MSi, Apt, as quoted from ugm.ac.id, said the results of his experiments performed on mice are known to leaf sambiloto contains the andrografolid, deoksiandrografolid, neoandrografolid, 14-Deoxy-didehidroandrografolid, and homoandro-grafolid.
Andrografolid with the main phytochemical components capable of lowering blood glucose levels and GLUT-4 expression in mice type 1 DM.
Research results are presented in the session Indonesia Industry Research Forum parallel to the 4th on 2012, it was recently done on mice. However, it is known the granting of isolates andrografolid or herbaceous extracts sambiloto terpurifikasi for five days showed the hypoglycemic activity of poten in mice of diabetes mellitus with insulin resistance. Both also lowered LDL levels poten and triglycerides, but not effect conferring against cholesterol levels and body weight of a rat.
The combination of metformin and as a result extracts show anti-cancer activity DM lower than his usage. Interestingly, his findings from andrografolid and extract sambiloto lowers blood glucose levels in mice DM type 2 insulin resistance through increased expression of GLUT4 protein in muscle tissue.
Sambiloto, as put forward Bambang Pujiasmanto, as long as it’s grown out in the open like fields, roadsides, cliffs, river or channel, shrubs, under trees or bamboo teak forest. Community harvest plant of native habitat.
He reminded, saw the need for traditional medicine as much as sambiloto 709.6 ton simplisia wet every year, it is necessary the effort of cultivating the plants cultivated plants become sambiloto.
Sambiloto is a row of plants that pocketed the benefits and health benefits for the body, this plant is actually already used to treat many diseases on our bodies … There have been many in consumption and the traditional herbs as medicines produced/jamu herbal medicine, in carrying carrying plants sambiloto is traditional Herbalism for the manufacture of major and very reliable to treat the illness complaints answered/patient complaining the doctor carrying medicinal herbs. Sambiloto is a row of plants that pocketed the benefits and health benefits for the body, this plant is actually already used to treat many diseases on our bodies … There have been many in consumption and the traditional herbs as medicines produced/jamu herbal medicine, in carrying carrying plants sambiloto is traditional Herbalism for the manufacture of major and very reliable to treat the illness complaints answered/patient complaining the doctor carrying medicinal herbs.
Plant Sambiloto very helpful as the main herbal remedy that can be relied upon to eradicate the disease in our body, with the herbal plant is very minimize side effects that occur in the body, the time consuming and treat, and even survey This herbal plant proves to be consumed each day, because it benefits from herbal plants in trust could help eradicate the disease and a very scary in our bodies, an example of a disease that was haunting us is diabetic.
As one of the herbal medicine this plant can be consumed in the long run, compared with the chemical drug Side effect conferring later in other organs.
The content of substances Sambiloto
Andrographolide, the Glycoside diterpen
MECHANISM OF ACTION
Andrographolide is the main active substance in sambiloto which serves to lower the levels of glucose in the blood.
According to research from the pharmaceutical Faculty et al Munawara UGM th 2004 sambiloto leaves stew that is able to lower the blood glucose levels of mice males.
Soedigdo dkk, ITB through his experiments on rabbits stated that andrographolide in extract of sambiloto proved to have hypoglycemic effect (lowering sugar levels in the blood).
Minggawati, th 1990, Faculty of pharmacy, University of Widya Mandala, through his experiments claimed that mixed extract of sambiloto: cat whiskers = 7:3 given orally is capable of lowering the levels of sugar in the blood.
Diabetes (Diabetes mellitus) is a disease characterized by blood sugar levels that exceed normal value, due to the body’s insulin deficiency either absolute or relative.
Advice And Prevention
1. Eat foods that contain lots of fiber.
Consumption of fruit and vegetables that contain lots of fiber, since fiber helps improve control of blood sugar and lower insulin requirements, so you can help diabetics.
2. A healthy lifestyle through proper nutrition.
It takes the right nutrition patterns, to be carried on a consistent basis and full of discipline.
3. Physical activity and sports.
Exercise can encourage the body to use insulin.
4. For smokers in order to quit smoking
Because nicotine can affect in a negative absorption of glucose by the cells.
Diabetes mellitus is derived from Greece, meaning roughly a pee (urine) taste is sweet like honey. Diabetes, urinary sugar, or Diabetes mellitus is caused by disruption of the function of the pancreas in producing insulin in the amount your body needs. The amount of insulin that is insufficient to result in sugar and carbs cannot be converted entirely into glycogen. Therefore, the levels of glucose in the blood. Glucose or sugar is then ejected along with urine (urine).
In addition to this herbal plant Sambiloto also pocketed a range efficacy, efficacy other plants and herbs from Sambiloto can help cure:
1. Basilar Dysentery
2. Dysentery Herbaceous fresh purslane (Portulaca oleracea).
3. Influenza, sore head, fever.
4. Whooping cough (pertussis),
5. Pneumonia, inflammation of the mouth,
6. Nose Slimy (rinorea),
7. Middle Ear Infection (OMA),
9. Typhoid fever
10. Sore throat
11. the malaria Drugs
Sambiloto often also called papahitan (), kioray, kipeurul, and tukilo (Sunda), Ziziphus mauritiana, sadilata, sambiloto and takila (Java). As well as hahasa in Indonesia sambiloto.
Sambiloto (Andrographlspaniculata, Ness)Sambiloto included in acanthaceae family.Sambiloto not native to Indonesia, but
allegedly originating from India. According to data of specimens in The Herbarium Bogoriense in Bogor, sambiloto already exists in lndonesia since 1893. All parts of this plant(herbaceous) is used as a traditional medicine. Efficacy This is a very bitter plant have been examined by the a number of experts from within or outside the country since the year 1980 ‘s. Even on 13 December 1986, sambiloto has been patented as anti-cancer drugs Immuno human Deficiency Virus (HIV) bypharmaceutical companies of Germany to hold joint research scientists from Bastyr University in Germany.
Type – the type of diabetes
1. Type I or TYPE 1 (Insulin Dependent Diabetes Mellitus)
Insulin-dependent diabetes, at this state of the pancreas gland is not able to produce insulin at all. In general suffered by people under the age of 30 years and most often at the age of 10 – 30th.
2. Type II or NIDDM (Non Insulin Dependent Diabetes Mellitus)
In general suffered by people over the age of 40 years and usually occurs in people with obesity (overweight). On this type of pancreas still works but shows a relative deficiency, so the body loses the ability to utilize insulin effectively.
3. DM that occurred during pregnancy.
The symptoms of Diabetes
-Frequent urination especially at night.
-Frequent thirst and hunger. — often feel sleepy, itching and tingling.
-Dry skin, ulcers arise easily, boils and sores hard to heal.
-Weight continues to decline and become thin.
-Quickly tired and was not powered.
-The passion of sex decreased.
-A pregnant woman who gave birth to her baby more than 4 kg.
Some symptoms of diabetes are many removing urine, often feel thirsty, and if there are wounds will be difficult once cured. In some cases, the disease often do not show symptoms. New sufferer realize after arising complications in organs of eye, kidney, heart, and nervous.
Given the very dangerous complications, diabetes should be solved as early as possible. With diet, exercise, and medication on a regular basis, however, these diseases can be reduced.
Andrographis paniculata or Sambiloto is one plant that has long been well known to have efficacy cure various diseases, including diabetes. Allegedly, this plant originates from India but its spread has expanded to various areas in Indonesia.
The chemical content of Herba Andrographidis among others: andrographolid, neoandrographolid,andrographolid, andrographoside, deoxy deoxy andrographoside, ninandrographolid, 74-11-deoxy-
oxoandrographolid, 14-deoxy-ll, 12-didehydroandrographholid,homoandmgrapholid. andrographan,andrographosterin, sitosterol-D-glucoside, flavonoids.The main components of Andmgrapholidmerupakan (2.39%) and main nutritious substances aMif in treatment diabetes mellitus. These compounds have a sense very bitter, chemical describe the structure of such a ring.
Extract of sambiloto nutritious herbs as hypoglycemic with how to prevent the absorption of of glucose from the intestines, if consumed shortly before eating.
In other fiteratur, mentioned that extracts ethanol sambiloto contain substances that are antidiabetic. Allegedly the mechanism is to How to improve the metabolism of glucose. The effect of hypotriglyceridemic that there are also very beneficial for diabetics.
If regular drinking sambiloto tea guarantee you will be free from diabetic